Iriban (Mebeverine Hydrochloride)

Therapeutic Group: Gastro Intestinal Disorders Irritable Bowel Syndrome

Iriban 135 tablet: Each tablet contains Mebeverine Hydrochloride BP 135 mg. Iriban SR 200 capsule: Each SR capsule contains Mebeverine Hydrochloride BP 200 mg.

Iriban is a musculotropic antispasmodic agent used to relieve cramps or spasms of the stomach and intestine (gut). It is particularly useful in treating irritable bowel syndrome (IBS) and similar conditions. It works by relaxing the muscles and helping restore the normal movement of the gut.

Iriban is indicated: For the symptomatic treatment of irritable bowel syndrome (IBS) Other conditions include: Chronic irritable colon Spastic constipation Mucous colitis Colicky abdominal pain Persistent non-specific diarrhoea

Adults, elderly and children over 10 years: 1 tablet three times, or 1 capsule twice daily Iriban is most effective when taken 20 minutes before meals. After several weeks when the desired effect has been obtained, the dosage may be gradually reduced. *Missed dose: If a dose of this medicine is missed, that should be taken as soon as possible. However, if it is almost time for the next dose, then skip the missed dose and the regular dosing schedule should be maintained. Dose should not be doubled at the same time to compensate the missed dose.

Generally Mebeverine is well tolerated. However, few side-effects like skin rash, urticaria and angioedema may appear.

Caution should be exercised in porphyria or allergic reaction to this or any other medicine of this group.

Not known

No teratogenicity has been shown in animal experiments. However, the usual precautions concerning the administration of any drug during pregnancy should be exercised. Mebeverine does not excrete in the breast milk after administering the therapeutic dose. Use in children Mebeverine is not recommended in children under 10 years. Drug Interaction Not known

On theoretical grounds it may be predicted that CNS excitability will occur in case of overdosage. No specific antidote is known: gastric lavage and symptomatic treatment is recommended.

Iriban 135 tablet: Each box contains 5 blister strips of 10 tablets. Iriban SR 200 capsule: Each box contains 3 blister strips of 10 capsules.